Exposure
Five lung carcinogens (cancer-causing-agents)
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The JEM is based on a quantitative exposure assessment approach.  The exposure rating is derived from a general population JEM (DOMJEM) assigning no, low or high exposure levels. Some modifications were made to DOM-JEM for the ratings for asbestos, PAH and RCS. The rating was changed from ‘no’ to ‘low’ exposure if the individual was employed in a particular industry where exposure was likely.

The JEM includes the following carcinogens:

  • Asbestos
  • Chromium-VI
  • Nickel
  • Polycyclic aromatic hydrocarbons (PAH)
  • Crystalline silica (RCS)

Name: SYNJEM

 

Demographics
Covers Canada and most of Europe
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The JEM includes quantitative estimates of the level of exposure by region (Canada; Central and Eastern European countries; France; Germany; Italy/Spain; Sweden (including data from all Nordic countries); the United Kingdom; and the Netherlands.) except for the exposure PAH.

Coverage
Occupational titles in Danish ISCO-88.

Calendar Period
1970-2020
Job Classification

The Danish version of The International Standard Classification of Occupations (DISCO-88).  ISCO-68 is also availeble.

Uncertainty in Exposure

The JEM is based on statistically modelling of a large amount of personal occupational exposure measurement data.

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References & JEM developer
Key Developer:Hans Kromhout

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Affiliation at the time of development: Department of Occupational and Environmental Medicine, Dep. of Population Health Sciences, University of Utrecht, Holland

Reference: SYN-JEM: A Quantitative Job-Exposure Matrix for Five Lung Carcinogens

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Peters, S., Vermeulen, R., Portengen, L., Olsson, A., Kendzia, B., Vincent, R., Savary, B., LavouCrossed Sign, J. D. S., Cavallo, D., Cattaneo, A., Mirabelli, D., Plato, N., Fevotte, J., Pesch, B., Brüning, T., Straif, K., & Kromhout, H. (2016). SYN-JEM: A Quantitative Job-Exposure Matrix for Five Lung Carcinogens. Annals of Occupational Hygiene, 60(7), 795–811. 

Inspiration from research projects on physical workload in DOC*X

Within DOC*X, several research projects investigate the relationship between carcinogens and health, based on the job-exposure matrix SYNJEM.

One of the projects specifically examines the risk of developing ischemic heart disease from occupational exposures, including carcinogens. It further explores whether long-term exposure to dust particles increases the risk of acute myocardial infarction and contributes to the progression of atherosclerosis in the coronary arteries.

These is just one example of the research conducted within the DOC*X framework. Here you can find more information on other research projects using DOC*X data.